Studies
Adjuvants
Vaccine adjuvants are chemical proteins that enhance the immune
response to vaccine antigens. 
AVMA Position
The AVMA Council on Biologic and Therapeutic Agents (COBTA) has
thoroughly reviewed information on dog and cat vaccines and has issued two
reports: 1. Principles of Vaccination - JAVMA Sept. 1, 2001 2.Report on Cat and Dog
Vaccines - JAVMA Nov. 15, 2002 
AAHA Canine Vaccination Guidelines
Limited published scientific information exists on duration of immunity.
Therefore, these guidelines and recommendations are based on limited scientific
evidence but are supported by consensus and expert opinion, as well as
clinical evidence.
AAFP Feline Vaccination Guidelines
Extended vaccination intervals recommended in the 2000 Report of the American Association
of Feline Practitioners (AAFP) and Academy of Feline Medicine Advisory Panel on
Feline Vaccines referenced a foundation study conducted by Dr. Fred Scott. 
Killed vs. Modified-Live Vaccines
For some antigens, veterinarians have to decide whether to use a
killed vaccine or a modified-live vaccine. Each vaccine has its advantages,
and each has its disadvantages. 
Recent Information: Three-Year Duration of Immunity Challenge Studies
Fort Dodge completed a long-term vaccination challenge study to determine
if three main canine antigens,canine distemper virus (CDV),canine adenovirus
type 2 (CAV-2) and canine parvovirus (CPV),protected for three years. 
Sarcomas
In 1996, the Vaccine Associated Feline Sarcoma Task Force was formed with the
mission of determining the cause of sarcomas in cats. 
The Important Role of Vaccine Adjuvants
Adjuvants are agents designed to stimulate the immune response
to vaccine antigens. 
